3-Amino-1-propanesulfonic acid CAS#3687-18-1

CAS Number: 8002-43-5
Chemical Formula: C3H9NO3S
Synonyms:

aminopropanesulfonicacid,3-aminopropanesulfonicacid
HOMOTAURINE
3-AMINOPROPANE-1-SULFONIC ACID

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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3-Amino-1-propanesulfonic acid CAS#3687-18-1

Homotaurine (also known as tramiprosate (INN), 3-amino-1-propanesulfonic acid, or 3-APS) is a natural sulfonic acid found in seaweed. Tramiprosate is a sulfated glycosaminoglycan mimetic that was reported to bind soluble Aβ and inhibit the interaction of Aβ with endogenous glycosaminoglycans, thereby preventing β-sheet formation. Conversely, tramiprosate was also reported to promote tau polymerization into fibrillar aggregates. It is also an analog of GABA that can act as a partial agonist of GABAA receptors, as well as an antagonist at GABAB receptors.

3-Amino-1-propanesulfonic acid Chemical Properties

Melting point	293 °C (dec.)(lit.)
density	1.202 (estimate)
refractive index	1.5130 (estimate)
storage temp.	2-8°C
solubility	Water (Slightly)
form	Crystalline Powder
pka	1.06±0.50(Predicted)
color	White to slightly blue
Cosmetics Ingredients Functions	SURFACTANT - HYDROTROPE SURFACTANT - CLEANSING
InChI	InChI=1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
InChIKey	SNKZJIOFVMKAOJ-UHFFFAOYSA-N
SMILES	C(S(O)(=O)=O)CCN
LogP	-4.555
CAS DataBase Reference	3687-18-1(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	UN2585
WGK Germany	1
HazardClass	8
HS Code	29049090
Storage Class	13 - Non Combustible Solids

Product Application Of 3-Amino-1-propanesulfonic acid CAS#3687-18-1

3-Amino-1-propanesulfonic acid is a Important gabamimetic agent-evokes neurological responses similar to those elicited by γ-aminobutyric acid (GABA). It is an intermediate in the synthesis of acamprosate. acamprosate is an alcohol addiction treatment commonly used to reduce urges to drink and help people in recovery remain sober.

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